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Updated: May 5, 2026

Cell-free Biochemical Fluorometric Enzymatic Assay for High-throughput Measurement of Lipid Peroxidation in High Density Lipoprotein
Published on: October 12, 2017
Lipoprotein (a): A biomarker of cardiovascular risk detectable in childhood
Walter Masson1, Juan P Nogueira1, Silvina Cuartas1
1Argentine Lipid Society, Autonomous City of Buenos Aires, Argentina.
Abstract:
Lipoprotein (a) [Lp(a)] is a lipoprotein similar to low-density lipoprotein (LDL), which binds to a characteristic component: apolipoprotein (a). The plasma Lp(a) level is mainly determined by genetic factors, with variations across ethnic groups. In adults, various epidemiological and genetic studies have shown that elevated Lp(a) levels are an independent risk factor for atherosclerotic cardiovascular disease and aortic valve stenosis, associated with inflammatory, atherogenic, and thrombotic mechanisms. Given that the distribution, variability, and prognostic value of this marker in the pediatric population have been less investigated, the objective of this review is to analyze the available evidence on the behavior of Lp(a) as a risk marker in children and adolescents, current recommendations for its measurement in pediatrics, and treatment prospects.
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