Related Experiment Video

Updated: Jun 13, 2026

A Proinflammatory, Degenerative Organ Culture Model to Simulate Early-Stage Intervertebral Disc Disease.
05:46

A Proinflammatory, Degenerative Organ Culture Model to Simulate Early-Stage Intervertebral Disc Disease.

Published on: February 14, 2021

Promoting intervertebral disc fusion using BMP2, L51P, and the EP4 agonist KMN-159: synergistic osteogenesis in human

Shuimu Chen1,2,3, Xinggui Tian4, Stefan Zwingenberger4

  • 1Department of Orthopaedic Surgery & Traumatology, Inselspital, Bern University Hospital, Faculty of Medicine, University of Bern, CH-3010, Bern, Switzerland.

European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
|March 3, 2026
PubMed
Abstract

No abstract available in PubMed .

Keywords:
Annulus fibrosus cellsBMP2KMN159L51POsteogenesisSpinal fusion

More Related Videos

Multilevel Oblique Lumbar Interbody Fusion in Degenerative Lumbar Disc Disease with Instability11:30

Multilevel Oblique Lumbar Interbody Fusion in Degenerative Lumbar Disc Disease with Instability

Published on: July 25, 2025

Lateral-PLIF for Lumbar Spinal Arthrodesis: A Detailed Step-By-Step Surgical Technique08:36

Lateral-PLIF for Lumbar Spinal Arthrodesis: A Detailed Step-By-Step Surgical Technique

Published on: January 23, 2026

Related Concept Videos

Degenerative Disc Disease I: Introduction01:27

Degenerative Disc Disease I: Introduction

Degenerative disc disease is a chronic condition in which intervertebral discs gradually lose structure and function. It is not infectious or autoimmune; rather, it results from age-related biochemical and mechanical changes, influenced by genetic, metabolic, and environmental factors.Structure and Function of DiscsThe spine contains 23 intervertebral discs that absorb load, distribute forces, maintain spacing, and allow flexibility. Each disc consists of a nucleus pulposus, a gel-like core...