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Partial Duodenal Obstructions: A National Surgical Quality Improvement Program Pediatric Analysis of Clinical Factors
Emma James1, Yumiko Gely1, Denise Danos2
1Department of Surgery, Louisiana State University Health Science Center, New Orleans, Louisiana.
Insights
Partial duodenal obstruction (PDO) is often diagnosed later and more common in males with developmental delays. These patients experienced higher rates of complications like readmission and sepsis following surgery.
Area of Science:
- Pediatric Surgery
- Gastrointestinal Surgery
- Neonatal Care
Background:
- Duodenal atresia is a common cause of intestinal obstruction in newborns.
- Partial duodenal obstructions (PDO) may present later with feeding intolerance.
- Identifying PDO characteristics is crucial for timely diagnosis and intervention.
Purpose of the Study:
- To identify patient characteristics associated with partial duodenal obstruction (PDO).
- To compare surgical outcomes between full duodenal obstruction and PDO.
- To inform early diagnosis and management of PDO.
Main Methods:
- Utilized the National Surgical Quality Improvement Program-Pediatric database.
- Compared patient demographics and surgical outcomes.
- Stratified patients by age at repair: before 180 days (full obstruction) vs. after 180 days (PDO).
Main Results:
- 138 of 2213 patients had PDO, diagnosed after 180 days.
- PDO patients were more likely male, with pulmonary/airway abnormalities, and developmental delay.
- PDO patients had higher rates of readmission, reoperation, organ space infection, and sepsis.
Conclusions:
- Partial duodenal obstruction (PDO) is associated with specific patient factors, distinct from full duodenal obstruction.
- PDO patients exhibit increased postoperative complications.
- Early recognition of PDO indicators is vital for improved surgical outcomes.
Introduction:
Duodenal atresia is one of the most common causes of intestinal obstruction, typically presenting in the first few days of life. Partial duodenal obstructions (PDO) can allow for the passage of liquids and may not be diagnosed in early infancy until feeding intolerance becomes more apparent. We aimed to identify characteristics of patients who may have PDO and describe their outcomes.
Methods:
Utilizing the National Surgical Quality Improvement Program-Pediatric database, patient characteristics and surgical outcomes were compared between patients who underwent operative repair for duodenal obstructions before 180 d (full duodenal obstruction) and after 180 d (PDO).
Results:
Of 2213 patients who underwent procedures for duodenal obstructions between 2012 and 2020, 138 were performed after 180 d (PDO). These patients were more likely to be male (66.7 versus 49.7%, P = 0.0001), have a structural pulmonary/airway abnormality (10.9 versus 2%, P < 0.0001), developmental delay (33.3 versus 12.2%, P < 0.0001), and undergo elective surgery (70.3 versus 43.7%, P < 0.0001). Patients who underwent surgery before 180 d (full duodenal obstruction) were more likely to have major cardiac risk factors (32.2 versus 12.3%, P < 0.0001) and birthweight <1500g (7.3 versus 0%, P = 0.0010). Readmission (11.7 versus 3.1%), reoperation (13.3 versus 4.1%), organ space infection (3.9 versus 0.3%), and sepsis (3.9 versus 1.6%) were more likely in patients undergoing procedures after 180 d (PDO) (P < 0.05).
Conclusions:
PDO appears more likely in patients without the characteristic cardiac risk factor comorbidities. Recognizing these factors will be important for timely surgical intervention to minimize postoperative complications.
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