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Related Concept Videos

Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Pneumothorax-II01:27

Pneumothorax-II

Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
Clinical Manifestations:
Radiological Investigation II: MRI and Ventilation Perfusion Scan01:30

Radiological Investigation II: MRI and Ventilation Perfusion Scan

Description
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
MRI uses magnetic fields and radiofrequency signals to distinguish between normal and abnormal tissues. This technology provides a more detailed diagnostic image than CT scans, enabling it to characterize pulmonary nodules, stage bronchogenic carcinoma, and evaluate inflammatory activity in...

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Related Experiment Video

Updated: Jun 24, 2026

Voluntary Breath-hold Technique for Reducing Heart Dose in Left Breast Radiotherapy
11:38

Voluntary Breath-hold Technique for Reducing Heart Dose in Left Breast Radiotherapy

Published on: July 3, 2014

Lung Dose and Pneumonitis Risk Following Five-Fraction Breast Radiotherapy.

Kristin A Ward1, Matthew J Case1, Matthew Thomas1

  • 1Department of Radiation Oncology, Emory University, Atlanta, GA, USA.

Journal of Medical Imaging and Radiation Oncology
|June 23, 2026
PubMed
Summary
This summary is machine-generated.

Higher lung radiation doses in five-fraction breast radiotherapy correlate with increased pneumonitis risk. Accelerated partial-breast irradiation or prone positioning may reduce this risk.

Related Experiment Videos

Last Updated: Jun 24, 2026

Voluntary Breath-hold Technique for Reducing Heart Dose in Left Breast Radiotherapy
11:38

Voluntary Breath-hold Technique for Reducing Heart Dose in Left Breast Radiotherapy

Published on: July 3, 2014

Area of Science:

  • Radiation oncology
  • Medical physics

Background:

  • Five-fraction breast radiotherapy is a common treatment for early-stage breast cancer.
  • Symptomatic pneumonitis is a potential side effect of radiation therapy to the chest.
  • Understanding lung dose-volume relationships is crucial for minimizing treatment toxicity.

Purpose of the Study:

  • To assess the association between lung radiation dose and symptomatic pneumonitis after five-fraction breast radiotherapy.
  • To identify strategies for reducing lung radiation exposure and associated risks.

Main Methods:

  • Retrospective analysis of 224 early-stage breast cancer patients treated with five-fraction radiotherapy (WBRT or APBI).
  • Evaluation of lung dose-volume parameters and their correlation with symptomatic pneumonitis (grade ≥2).
  • Analysis of potential dose thresholds for increased pneumonitis risk.

Main Results:

  • Symptomatic pneumonitis occurred in 3.6% of patients, mostly mild and self-limiting.
  • Increased lung V8Gy, V10Gy, and V20Gy were significantly associated with higher pneumonitis risk (p<0.05).
  • A V20Gy threshold of 7.5% identified patients at higher risk (9.0% vs 0.7%).
  • Prone positioning for WBRT and APBI were associated with reduced lung V20Gy.

Conclusions:

  • Symptomatic pneumonitis risk increases progressively with higher fractional lung doses in five-fraction breast radiotherapy.
  • Accelerated partial-breast irradiation or prone positioning may mitigate lung dose and reduce pneumonitis risk in select patients.