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Published on: May 11, 2015
[Lung Cancer with Pulmonary Embolism: Evidence-based Progress in Anticoagulation Assessment and Management]
Yiming Ma1,2, Kun Liu1,2, Changling Tu1,2
1Department of Geriatric Oncology, The Third Affiliated Hospital of Kunming Medical University, Yunnan Cancer Hospital, Peking University Cancer Hospital Yunnan, Kunming 650118, China.
Zhongguo Fei AI Za Zhi = Chinese Journal of Lung Cancer
|March 4, 2026
Summary
Lung cancer patients have a high risk of venous thromboembolism (VTE), especially pulmonary embolism (PE). This review addresses challenges in assessing VTE and bleeding risks, guiding anticoagulation and prevention strategies for better patient outcomes.
Area of Science:
- Oncology
- Hematology
- Clinical Medicine
Background:
- Lung cancer is a leading cause of cancer mortality worldwide.
- Patients with lung cancer have a significantly elevated risk of venous thromboembolism (VTE), including pulmonary embolism (PE).
- VTE complicates lung cancer treatment, increasing mortality, morbidity, and healthcare costs.
Purpose of the Study:
- To review current clinical risk assessment strategies for VTE and bleeding in lung cancer patients.
- To summarize anticoagulation management, including drug selection and special population considerations.
- To outline secondary prevention methods for PE in this patient group.
Main Methods:
- Comprehensive literature review of existing studies on VTE, bleeding, and anticoagulation in lung cancer.
- Analysis of current risk assessment models and their limitations.
- Synthesis of evidence regarding anticoagulant therapies and preventative measures.
Main Results:
- Existing risk assessment tools for PE and bleeding in lung cancer patients have limited efficacy.
- Anticoagulation management is complex, involving drug interactions and specific patient populations.
- Individualized treatment strategies are crucial for effective VTE and bleeding management.
Conclusions:
- Effective management of VTE and bleeding in lung cancer requires addressing limitations in current risk assessment.
- Optimizing anticoagulation and implementing secondary prevention are vital for improving patient survival and quality of life.
- This review provides a reference for personalized clinical decision-making in lung cancer patients with PE.
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