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Updated: Jun 5, 2026

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Vulvar Metastasis from Breast Cancer Treated with Abemaciclib plus Fulvestrant: A Case Report
Clémence Vanden Berghe1, Andoni Laka Antxustegi2, Nicole Nicaise1
1CHU UCL Namur Site Sainte-Elisabeth, Namur, Belgium.
This case study highlights successful treatment of rare vulvar metastasis from breast cancer using cyclin-dependent kinases 4 and 6 (CDK4/6) inhibitors and fulvestrant, achieving complete remission after 17 years. Long-term follow-up is crucial for hormone-sensitive breast cancer patients.
Area of Science:
- Oncology
- Gynecologic Oncology
- Breast Cancer Research
Background:
- Vulvar cancer is rare, accounting for less than 1% of female cancers.
- Metastatic vulvar tumors are even rarer, representing 5-8% of vulvar cancers.
- Breast cancer can rarely metastasize to the vulva.
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