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Updated: May 4, 2026

Assessment of Kidney Function in Mouse Models of Glomerular Disease
Published on: June 30, 2018
Reno-protective mechanisms of curcumin in diabetic nephropathy
Qi Wei1,2, Yang Liu3, Wen-Hui Wu4
1Department of Nephrology, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300382, China.
Abstract:
Curcumin has a pivotal role in diabetic nephropathy (DN), intervening in its progression through molecular, pathological, and clinical levels. This review systematically summarizes how curcumin modulates multiple pathways, ameliorates pathological alterations, and improves the metabolic disorders in DN. However, its clinical efficacy is constrained by low bioavailability. Consequently, this work provides novel perspectives for the multidimensional intervention of DN and offers strategies for optimizing drug delivery systems.
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