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Assessment of the Metabolic Profile of Primary Leukemia Cells
Published on: November 21, 2018
Chronic myeloid leukaemia (CML) presenting as asymptomatic leukocytosis in pregnancy
Sowmya Koteshwara1, Krishna Madhuri Gadde2, Mahesh Rajashekaraiah3
1OBG, JSS ACCADEMY OF HIGHER EDUCATION AND RESEARCH, Mysuru, Karnataka, India sowmyak@jssuni.edu.in.
Although mild leukocytosis is common in pregnancy, markedly elevated counts warrant prompt evaluation to exclude pathological causes such as infections and leukaemia. Chronic myeloid leukaemia (CML) is a chronic myeloproliferative condition increasingly being seen in younger age groups.Here we report a woman in her early 30s with asymptomatic marked leukocytosis at term, subsequently diagnosed with CML. As she was near term, she was managed conservatively through delivery before initiation of definitive therapy postpartum. This case underscores the importance of baseline and serial leucocyte monitoring in pregnancy and highlights the unique therapeutic challenges of managing CML during pregnancy.
Although mild leukocytosis is common in pregnancy, markedly elevated counts warrant prompt evaluation to exclude pathological causes such as infections and leukaemia. Chronic myeloid leukaemia (CML) is a chronic myeloproliferative condition increasingly being seen in younger age groups.Here we report a woman in her early 30s with asymptomatic marked leukocytosis at term, subsequently diagnosed with CML. As she was near term, she was managed conservatively through delivery before initiation of definitive therapy postpartum. This case underscores the importance of baseline and serial leucocyte monitoring in pregnancy and highlights the unique therapeutic challenges of managing CML during pregnancy.
