Related Experiment Video
Updated: Mar 6, 2026
07:13
Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
Published on: April 12, 2021
5.3K
A Multidimensional Framework for Pharmaceutical Care to Enhance Medication Adherence and Patient Engagement: The
Ramón Morillo-Verdugo1, Olatz Ibarra-Barrueta2, Maria Teresa Martin Conde3
1Pharmacy Department, Virgen de Valme University Hospital, South Seville Health District, Seville, Spain.
Patient Preference and Adherence
|March 5, 2026
Summary
The Capacity-Motivation-Opportunity MAPEX (CMO-MAPEX) framework enhances medication adherence support in outpatient pharmaceutical care by integrating patient factors and care context. This patient-centered approach tailors interventions for improved treatment management.
Area of Science:
- Pharmaceutical Care
- Health Services Research
- Behavioral Science
Background:
- Medication adherence is critical for effective treatment outcomes in outpatient settings.
- Existing frameworks often lack a multidimensional, patient-centered approach to adherence support.
- Integrating behavioral determinants and patient experience is essential for optimizing pharmaceutical care.
Purpose of the Study:
- To develop the Capacity-Motivation-Opportunity MAPEX (CMO-MAPEX) framework.
- To create a multidimensional, patient-centered, and operational guide for medication adherence support.
- To translate adherence theory into practical application within outpatient pharmaceutical care.
Main Methods:
- A six-stage framework development process including narrative scoping synthesis and expert panel review.
- Analysis of behavioral, experiential, and organizational determinants of medication adherence.
- Integration of adherence evidence, treatment burden, patient experience, and hybrid-care models.
Main Results:
- A three-domain structure (Capacity, Motivation, Opportunity) was identified, capturing key adherence factors.
- The framework operationalizes these domains through assessment, stratification, interventions, and hybrid follow-up.
- Patient-reported outcomes and experience measures are integrated for dynamic care adjustment.
Conclusions:
- CMO-MAPEX offers a pragmatic and scalable solution for medication adherence support.
- It translates adherence theory into patient-centered pharmaceutical care.
- The framework enables reproducible tailoring of adherence support based on patient complexity and preferences.
Related Concept Videos
01:28Drug Therapy
346
The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Antianxiety Medications
346
01:15Drug Dosing: Geriatric Patients
328
Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
328
01:26Oral Drug Delivery Systems: Continuous-Release Systems
104
Continuous-release drug delivery systems offer a strategic approach to maintaining therapeutic drug levels over extended periods following oral administration. By modulating the release rate of active pharmaceutical ingredients, these systems minimize fluctuations in plasma concentrations, which enhances clinical efficacy and reduces the need for frequent dosing. Such characteristics make them particularly advantageous in managing chronic diseases where patient adherence and stable drug...
104
01:15Methods of Documentation VI: Case Management Model
992
The case management model is a multidisciplinary approach that involves healthcare professionals from diverse disciplines, such as physicians, nurses, therapists, social workers, and pharmacists, working collaboratively to address the various needs of patients. Each healthcare professional brings unique expertise and perspectives, contributing to a more comprehensive understanding of the patient's condition and tailoring treatment plans accordingly.
For example, a patient with a chronic...
For example, a patient with a chronic...
992
01:13Patient-centered Care
3.2K
Patient-centered care involves delivering care beyond inpatient hospitalization. Reflective practice can enhance a patient-centered approach. Reflective practice is a process of reasoning that considers all aspects of the present situation, including practicalities, learning from personal practice, and consideration of patient needs. Patients appreciate care decisions made while considering their input. Involving the patient in their care provides the patient with a sense of contribution rather...
3.2K
01:29Therapeutic Drug Monitoring: Affecting Factors
299
Therapeutic Drug Monitoring (TDM) is the clinical practice of measuring specific drug levels in a patient's blood or body tissues to manage and optimize therapy. TDM is crucial for drugs with narrow therapeutic windows, like warfarin and phenytoin, where incorrect doses can lead to treatment failure or severe side effects. This monitoring ensures the dosage administered is within a safe and effective range. The factors affecting therapeutic drug monitoring include:Patient-Specific Factors:a.
299