[(Chemo-)Preventive strategies for skin cancer: current state of knowledge and implications for daily practice]

In view of rising incidence rates worldwide, the prevention of skin cancer is a central pillar of public health. While UV protection forms the basis of primary prevention, pharmacological strategies (chemoprevention) are becoming increasingly important. This paper provides a practice-oriented synthesis of current evidence, ranging from behavioural prevention and systemic approaches with nicotinamide and retinoids to experimental strategies such as immune checkpoint inhibitors and DNA repair enzymes.