Intact Fish Skin Grafting in a Patient With Hidradenitis Suppurativa

Area of Science:

• Regenerative Medicine
• Dermatology
• Wound Healing

Background:

• Hidradenitis Suppurativa (HS) presents complex wound management challenges, including infection and poor circulation.
• Traditional treatments like autografting carry risks such as donor site morbidity.
• Chronic wounds in HS patients often lead to prolonged hospitalization and reduced quality of life.

Purpose of the Study:

• To evaluate the efficacy of intact fish skin xenografts in managing chronic wounds associated with Hidradenitis Suppurativa (HS).
• To explore a novel therapeutic option for non-healing HS wounds.

Main Methods:

• A case report detailing the treatment of a 35-year-old female patient with HS affecting bilateral axillary regions.
• Application of intact fish skin grafting (Kerecis™) after surgical incision and drainage procedures.
• Monitoring wound healing, granulation tissue formation, and wound edge approximation.

Main Results:

• The patient exhibited significant granulation tissue deposition following fish skin grafting.
• Successful wound edge approximation was observed, indicating effective wound healing.
• The treatment facilitated natural tissue regeneration in the chronic HS wounds.

Conclusions:

• Intact fish skin grafting is a promising and viable treatment option for non-healing wounds, specifically those associated with Hidradenitis Suppurativa.
• This xenograft approach can be effectively integrated into existing surgical and wound care protocols for HS patients.
• Fish skin xenografts offer a novel solution for promoting natural tissue regeneration in challenging chronic wound cases.