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Machine learning model integrating oral microbiota and clinical features for predicting osteoporosis and bone loss in

Jian Wang1, Fen Yang1, Sifan Hao1

  • 1West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, Sichuan, 610041, China.

BMC Microbiology
|March 5, 2026
PubMed
Abstract

No abstract available in PubMed .

Keywords:
Bone lossHigh-altitudeMachine learningOral microbiotaOsteoporosisTibetan populationTooth brush frequency

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Bone Disorders01:29

Bone Disorders

Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...

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