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Updated: Mar 7, 2026
Intratibial Osteosarcoma Cell Injection to Generate Orthotopic Osteosarcoma and Lung Metastasis Mouse Models
Published on: October 28, 2021
[Retracted] Knockdown of MALAT1 inhibits osteosarcoma progression via regulating the miR‑34a/cyclin D1 axis
Guangchao Duan1, Chuanlin Zhang1, Changke Xu1
1Department of Spine Surgery, Shangqiu First People's Hospital, Shangqiu, Henan 476100, P.R. China.
Abstract:
Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that certain of the β‑actin control bands shown in Fig. 6D on p. 25 had already been submitted for publication to a different journal in an article written by different authors at different research institutes. In addition, it was also identified that invasion assay data in Fig. 4D and western blot data in Fig. 5E also subsequently appeared in articles in other journals that were written by different authors at different research institutes. Given that the abovementioned contentious data in Fig. 6D had already been submitted for publication elsewhere prior to the submission of this paper to International Journal of Oncology, the Editor has decided that this paper should be retracted from the Journal. The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused. [International Journal of Oncology 54: 17‑28, 2019; DOI: 10.3892/ijo.2018.4600].
Insights
This paper has been retracted due to concerns about duplicated data. Specifically, beta-actin control bands and assay data appeared in other publications before this submission.
Area of Science:
- Oncology
- Biochemistry
Background:
- Concerns were raised regarding the duplication of scientific data.
- Specific figures (Fig. 6D, 4D, 5E) showed data that had been previously submitted or published elsewhere.
Purpose of the Study:
- To address concerns about data integrity and potential scientific misconduct.
- To evaluate the validity of the published findings in light of duplicated data.
Main Methods:
- Review of submitted figures and comparison with previously published data.
- Investigation of data duplication across multiple figures and research articles.
Main Results:
- Beta-actin control bands in Fig. 6D were found to have been submitted for publication previously.
- Invasion assay data (Fig. 4D) and western blot data (Fig. 5E) were also identified in other publications.
- Authors did not provide a response to the editorial office regarding these concerns.
Conclusions:
- The paper is retracted from the International Journal of Oncology due to data duplication issues.
- The integrity of the study's findings is compromised by the identified data reuse.
- The editorial office apologizes for any inconvenience caused to the readership.
