Related Experiment Video
Updated: Mar 7, 2026
![Assessment of Gastric Emptying in Non-obese Diabetic Mice Using a [13C]-octanoic Acid Breath Test](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F50301.jpg&w=3840&q=50)
Assessment of Gastric Emptying in Non-obese Diabetic Mice Using a [13C]-octanoic Acid Breath Test
Published on: March 23, 2013
Comparing Black Coffee to Coffee With Creamer in Gastric Emptying Time: A Nonrandomized Control Trial
Killian M Pache1, W Garrett Haffke1, Alexander W Estright1,2
1From the Case Western Reserve University School of Medicine, Cleveland, Ohio.
Adding creamer to coffee does not significantly delay gastric emptying time. This finding suggests current preoperative fasting guidelines may need revision for patients consuming coffee with creamer.
Area of Science:
- Anesthesiology
- Gastroenterology
- Preoperative Medicine
Background:
- Current preoperative fasting guidelines often classify coffee with creamer as a non-clear liquid, requiring a 6-hour fast.
- Limited evidence supports these extended fasting times, leading to frequent case delays and cancellations.
- This study investigates the impact of creamer on gastric emptying compared to black coffee.
Purpose of the Study:
- To determine if adding creamer to coffee significantly delays gastric emptying beyond the 2-hour clear liquid fasting period.
- To provide evidence for revising current preoperative fasting recommendations.
Main Methods:
- A nonrandomized control trial with alternating assignment was conducted.
- Healthy volunteers consumed either 16 ounces of black coffee or 16 ounces of coffee with two standard half-and-half creamers.
- Gastric emptying was assessed hourly using scans until a grade zero antrum was achieved.
Main Results:
- No significant difference in gastric emptying times was observed between black coffee and coffee with creamer groups.
- After 2 hours, 94% of the black coffee group and 97% of the coffee with creamer group had empty stomachs.
- All participants in both groups had empty stomachs within 3 hours.
Conclusions:
- Adding two standard half-and-half creamers to 16 ounces of coffee does not clinically alter gastric emptying times in healthy volunteers.
- These findings support the need for evidence-based reevaluation of preoperative fasting guidelines for coffee with creamer.
- Current 6-hour fasting recommendations for coffee with creamer may be unnecessarily restrictive.
Related Concept Videos
Gastric Emptying
Gastric Motility
Peristaltic Waves and Chyme Formation
Upon food entry, the stomach initiates...
One-Compartment Open Model for IV Bolus Administration: Estimation of Elimination Rate Constant, Half-Life and Volume of Distribution
Gastric Phase of Digestion
When food enters the stomach, it stretches the stomach walls and activates stretch receptors. This triggers local reflexes of the enteric nervous system, mediated through the myenteric plexus. These...
One-Compartment Open Model for IV Bolus Administration: Estimation of Clearance
In the one-compartment open model for intravenous (IV) bolus administration, clearance is estimated by dividing the elimination rate by the plasma drug concentration. This equation leverages the elimination rate constant and the apparent...
Noncompartmental Analysis: Mean Transit, Absorption and Dissolution Time
One of the key parameters is the mean transit time (MTT), which refers to the total duration required for drug molecules to transit through the body. MTT is determined by calculating the ratio of the area under the moment curve to the area...

