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Updated: Mar 7, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
Case of generalized morphea complicated with systemic sclerosis
Soichiro Sawamura1, Katsunari Makino1, Hitomi Nakashima1
1Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto.
Abstract:
Dear Editor, Localized scleroderma (LSc; morphea) is a rare fibrosing disease of the skin and underlying tissues, which is different from systemic sclerosis (SSc). LSc is classified based on clinical presentations: circumscribed, linear, generalized, pansclerotic, and mixed morphea. Generalized morphea (GM), which is characterized by widespread skin lesions with multiple indurated plaques or hyperpigmentation, is a relatively rare subtype occurring in 7-9% of patients with LSc. Previous studies have shown that SSc can be complicated by GM, separately from GM-like SSc. Here, we present a rare case of coexistence of LSc and SSc in which LSc skin lesions appeared before SSc became apparent. [...].
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