The study of the deposition process of bambus[6]uril on the porous TiNi surface using various physical methods

This study investigates new composite porous titanium nickelide-based materials, which have been obtained for the first time by functionalizing their surface with a promising macrocyclic compound-bambus[6]uril. Such functionalization aims to enhance the hemocompatibility and cytocompatibility of bone implants, addressing issues of uncontrolled drug release and poor implant integration. The surface modification was carried out by applying bambus[6]uril in the form of a dispersion using various physical methods such as immersion, vacuum treatment, and ultrasonic exposure. The obtained materials were characterized using IR spectroscopy, synchronous thermal analysis, and electron microscopy. The results of the study demonstrated that the highest cytocompatibility was observed in the samples obtained using vacuum and ultrasonic methods, while the samples modified using immersion exhibited cytocompatibility comparable to that of the control samples, which is attributed to the distribution pattern of bambus[6]uril molecules on the porous TiNi surface.