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Updated: Mar 8, 2026

Basophil Activation Test for Allergy Diagnosis
Published on: May 31, 2021
7 for 11: Food allergy treatment therapies
Arjola Cosper1, J Andrew Bird1
1Division of Allergy and Immunology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas.
Recent advances in managing IgE-mediated food allergy include new biologic therapies, immunotherapy, and dietary strategies. These proactive approaches offer alternatives to strict avoidance for affected individuals, especially children.
Area of Science:
- Allergy and Immunology
- Pediatric Allergy
- Clinical Therapeutics
Background:
- IgE-mediated food allergy impacts up to 10% of the population, causing significant morbidity, particularly in children.
- Traditional management focused on strict avoidance, but therapeutic strategies are evolving.
- Recent developments reflect a shift towards proactive management.
Purpose of the Study:
- To review recent advances in biologic therapies for food allergy.
- To highlight emerging immunotherapy modalities.
- To discuss novel dietary strategies in food allergy management.
Main Methods:
- Focused review of recent literature and clinical developments.
- Content based on presentations from the ACAAI 2025 Annual Meeting.
- Selection of emerging developments relevant to practicing allergists.
Main Results:
- Biologic therapies show promise in managing IgE-mediated food allergies.
- Immunotherapy modalities are advancing, offering new treatment options.
- Dietary strategies are evolving beyond simple avoidance.
Conclusions:
- Proactive therapeutic strategies are increasingly important in food allergy management.
- Biologics, immunotherapy, and dietary changes represent key areas of advancement.
- These developments offer new hope for patients with food allergies, especially children.
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