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Assessing Pediatric Sedation Using Patient-Centered Outcomes

Kristin D Sweeney Marso, Jin Peng, Beau D Meyer

    Anesthesia Progress
    |March 6, 2026
    PubMed

    Insights

    Pediatric dental sedation success was approximately 69.3%, with older age, male sex, and cooperative behavior predicting better outcomes. Combination sedation regimens did not improve success rates.

    Area of Science:

    • Pediatric Dentistry
    • Sedation Anesthesia
    • Patient-Centered Outcomes

    Background:

    • Dental anxiety is common in young children, often necessitating sedation for treatment.
    • Evaluating sedation success through patient-centered outcomes is crucial for optimizing pediatric dental care.

    Purpose of the Study:

    • To assess the success of pediatric dental sedation using patient-centered outcomes.
    • To analyze success rates for behavior, safety, and treatment independently and overall.

    Main Methods:

    • A cross-sectional study analyzed clinical data from 824 children aged 24-60 months undergoing first-time dental sedation.
    • Outcomes included behavior (Frankl score), safety (vital signs), and treatment success.
    • Logistic regression identified predictors of overall sedation success.

    Main Results:

    • Overall sedation success was 69.3% (behavior 49.0%, safety 79.5%, treatment 62.1%).
    • Oral midazolam showed higher behavioral and safety success than intranasal.
    • Older age, male sex, and cooperative presedation behavior significantly increased overall success odds.

    Conclusions:

    • Pediatric dental sedation success rates vary, with behavior being the least successful outcome.
    • Sedation regimen complexity (number of medications) did not impact success.
    • Patient factors like age, sex, and presedation cooperation are key predictors of successful dental sedation.
    Abstract

    Keywords:
    Dental care for childrenIntranasal sedationModerate sedationNitrous oxideOral sedationPediatric dentistry

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