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Updated: Mar 8, 2026

In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses
Published on: March 30, 2015
Percutaneous nephrostomy guidance by a convolutional-neural-network-based optical coherence tomography endoscope.
Chen Wang1, Paul Calle2, Feng Yan1
1Stephenson School of Biomedical engineering, University of Oklahoma, Norman, OK, 73019, USA.
This study introduces an endoscopic optical coherence tomography probe for safer kidney access surgery. It accurately identifies renal tissues and detects blood flow, improving percutaneous nephrostomy procedures.
Area of Science:
- Urology
- Medical Imaging
- Surgical Navigation
Background:
- Percutaneous nephrostomy is a common urological intervention.
- Challenges include precise needle placement and avoiding hemorrhage from blood vessel rupture.
Purpose of the Study:
- To develop an endoscopic optical coherence tomography (OCT) probe for enhanced needle navigation during percutaneous nephrostomy.
- To improve the safety and accuracy of kidney access surgeries.
Main Methods:
- Development of an endoscopic OCT probe for real-time imaging.
- Experiments conducted on thirty-one human kidneys for tissue and blood vessel analysis.
- Utilization of deep learning models (Inception and nnU-net) for automated recognition.
Main Results:
- Effective distinction of renal tissues (cortex, medulla, calyx, sinus fat, pelvis) using structural OCT imaging.
- Successful detection of renal blood flow via OCT Doppler function.
- High accuracy achieved: 99.6% for tissue classification (Inception) and 0.8917 IoU for blood vessel detection (nnU-net).
Conclusions:
- Endoscopic OCT probe enables precise identification of renal structures and blood vessels.
- Deep learning integration automates recognition, enhancing procedural safety.
- This technology offers significant potential to improve percutaneous nephrostomy outcomes.
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