Related Experiment Video
Updated: Mar 9, 2026
Experimental Human Pneumococcal Carriage
Published on: February 15, 2013
Epidemiological Burden and Hospitalization Trends of Human Metapneumovirus in Spain (2016-2023): A Retrospective
Oscar Brochado-Kith1,2, Ruth Gil-Prieto3,4, Angel Gil-de-Miguel1,5
1Department of Medical Specialities and Public Health, Rey Juan Carlos University, Av. Atenas S/N, 28922, Alcorcón, Madrid, Spain.
Introduction:
The hospitalization burden of human metapneumovirus (HMPV) in Spain was estimated assessing disease manifestations and risk factors to guide future vaccine strategies.
Methods:
This study was a retrospective analysis of Spain's National Hospital Data System (CMBD) from 2016-2023, performed using ICD-10-CM diagnosis codes, with age-stratified analyses for children under 6 years and adults over 60 years, assessing comorbidities and associated mortality risks.
Results:
A total of 4824 hospitalizations were identified; 75% in children, 16% in older adults. Bronchiolitis dominated in children while pneumonia was most common in older adults. Overall annual hospitalization rate was 18.70 hospitalizations per 100,000 in children up to 5 years old, and the annual hospitalization rate was 0.79 hospitalizations per 100,000 in adults over 60 years, Hospital costs totaled over €22 million, and, beyond this overall burden, expenditures showed a significant year-on-year increasing trend. There were 2 deaths among children < 6 years, 18 in individuals between 16 and 59 years and 74 in adults over 60 years old, reaching a case fatality rate of 9.65% in adults, with higher risk associated with kidney failure, liver disease, and cancer.
Conclusions:
HMPV poses a significant burden on vulnerable groups in Spain. Despite underdiagnosis, rising cases post-COVID highlight the need for targeted prevention. These findings offer a foundation for public health planning and vaccine prioritization.
More Related Videos
Related Concept Videos
01:30Pneumonia I: Introduction
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
01:30Pneumonia V: Nursing management and Prevention
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
01:29Pneumonia II: Pathophysiology
01:28Pneumonia IV: Management
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
01:30Pneumonia III: Complications and Assessment