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How Chronic Diseases Shape Subjective Life Expectancy: The Role of Pain
Mingming Liu1, Sze Him Isaac Leung2, Yuting Xia3
1Research Department of Epidemiology and Public Health, University College London, London, United Kingdom.
New chronic diseases significantly lower subjective life expectancy (SLE), with pain partially mediating this decline. Early interventions after diagnosis are crucial for managing SLE and improving long-term well-being in individuals with chronic conditions.
Area of Science:
- Gerontology
- Public Health
- Epidemiology
Background:
- Chronic diseases represent a significant global health burden.
- Subjective life expectancy (SLE) is an emerging indicator linked to health outcomes.
- The relationship between chronic disease patterns and SLE requires further investigation.
Purpose of the Study:
- To examine the association between chronic disease patterns and SLE.
- To explore the mediating role of pain in these associations.
Main Methods:
- Longitudinal study using 4 waves of the China Health and Retirement Longitudinal Study (CHARLS).
- Included 4774 participants aged 45 and older.
- Analyzed chronic disease patterns (none, preexisting, new-onset) and SLE using weighted mixed-effects logistic regression and mediation analysis.
Main Results:
- Most chronic diseases were associated with lower SLE; exceptions included dyslipidemia and certain neurological conditions.
- New-onset chronic diseases generally showed stronger associations with lower SLE than preexisting conditions.
- Pain partially mediated the relationship between chronic disease patterns and SLE.
Conclusions:
- Findings underscore the impact of chronic diseases on SLE, particularly new-onset conditions.
- Early intervention following diagnosis is vital for mitigating SLE decline.
- Pain management is a critical component for supporting long-term well-being in individuals with chronic diseases.
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