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"Within-Trial" Prognostic Score Adjustment Is Targeted Maximum Likelihood Estimation

Emilie Højbjerre-Frandsen1,2, Alejandro Schuler3

  • 1Biostatistics Methods, Novo Nordisk A/S, Søborg, Denmark.

Pharmaceutical Statistics
|March 9, 2026
PubMed
Abstract

Keywords:
causal inferenceprognostic scoresrandomized trialstargeted learning

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