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Author Spotlight: Innovations in iTUG Test for Enhanced Risk Assessment and Cognitive Insights
Published on: October 25, 2024
Brief Instrumented Mobility Testing Improves Fall Risk Stratification in Older Emergency Department Patients
Brian Suffoletto1, Nick Ashenburg1, Michael Losak1
1Department of Emergency Medicine, Stanford University, Stanford, California, USA.
Background:
Emergency department (ED) fall-risk screening often relies on measures that incompletely capture body movement signals relevant to future falls.
Objective:
Test whether inertial measurement unit (IMU) features from a brief, modified, instrumented Timed Up and Go (miTUG) provide incremental prognostic value for 6-month falls after ED discharge beyond a clinical screening tool.
Methods:
We conducted a prospective cohort study of community-dwelling adults ≥ 60 years discharged from an urban academic ED (September 2023-May 2024). Before discharge, participants completed a miTUG; four IMU features (sit-to-stand dominant frequency and duration; turn-to-sit spectral power and dominant frequency) were added to nine clinical predictors. The primary outcome was any fall within 180 days (6 months). Model performance was assessed using discrimination (AUC/C-index) and operating characteristics at ED-relevant thresholds. Secondary analyses examined models predicting time to first fall. Exploratory analyses examined patient sub-groups that may benefit from additional testing.
Results:
Among 360 participants, 94 (26.1%) fell within 180 days. The combined clinical+IMU model demonstrated modestly improved discrimination compared with the clinical-only model (AUC 0.72 vs. 0.67; Wilcoxon p = 0.19). At a prespecified 30% fall risk threshold, addition of IMU features improved sensitivity (0.57 vs. 0.45), specificity (0.80 vs. 0.76) and positive predictive value (0.50 vs. 0.39). In time-to-event analyses, the combined clinical+IMU model showed higher concordance (C-index 0.73 vs. 0.69) and better fit (likelihood-ratio p = 0.0006). Incremental gains were largest among adults ≥ 70 years, those with a recent prior fall, and those classified as lower risk by the clinical screen.
Conclusions:
In older adults discharged from the ED, IMU features from a brief, mobility assessment added modest improvements in fall risk stratification beyond a clinical screen. These findings are hypothesis-generating and support the need for external validation and implementation studies before clinical adoption.
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