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Clear Aligner Therapy in Adults With Stage II-IV Periodontitis: A Narrative Review
Sunil Kumari1, Greeshma Gothankar2,3, Nithin Kv4
1Orthodontics and Dentofacial Orthopedics, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.
Cureus
|March 10, 2026
Summary
Clear aligner therapy (CAT) can effectively treat adults with stage II-IV periodontitis, improving tooth alignment and migration. This approach requires careful integration with supportive periodontal care and interdisciplinary management for successful outcomes.
Area of Science:
- Dentistry
- Orthodontics
- Periodontology
Background:
- Stage II-IV periodontitis often causes pathologic tooth migration and occlusal instability, necessitating interdisciplinary care.
- Adults with periodontitis are increasingly seeking clear aligner therapy (CAT), but its role in periodontal treatment is not well-defined.
Purpose of the Study:
- To review existing clinical evidence on the use of CAT in adults with stage II-IV periodontitis.
- To outline principles for managing these cases through interdisciplinary care.
Main Methods:
- A narrative review of clinical studies was performed using major scientific databases.
- Included studies focused on adults with periodontitis or a stable reduced periodontium treated with CAT within an interdisciplinary framework.
Main Results:
- Nine studies (case reports, series, pilot study) met the criteria, involving patients with stage II-IV periodontitis.
- CAT was initiated after periodontal infection control and supportive periodontal care (SPC).
- In stable patients, CAT improved occlusal relationships and pathologic tooth migration without compromising periodontal health; fixed appliances showed no superiority.
Conclusions:
- Clear aligner therapy is a viable orthodontic option for adults with stage II-IV periodontitis when integrated into a structured interdisciplinary protocol.
- Further high-quality prospective studies are needed to validate these findings.
Keywords:
clear aligner therapyinterdisciplinary treatmentorthodontic treatmentpathologic tooth migrationperiodontitis
