Oral Manifestations of Secondary Syphilis

Syphilis is a chronic infectious disease caused by Treponema pallidum. It has resurfaced over the past years and remains a significant global public health problem. Its clinical presentation varies by stage, and oral lesions can be difficult to diagnose because they often resemble other pathologies. We report the case of a 28-year-old man presenting with indolent oral lesions, hoarseness, and dysphagia. A firm right-sided lymph node was also noted. Serological tests confirmed secondary syphilis. The patient received intramuscular benzathine penicillin G, leading to complete resolution of the lesions. Oral manifestations of secondary syphilis can present with diverse and nonspecific lesions, requiring careful clinical evaluation and appropriate serological testing for accurate diagnosis.