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Visual language model-assisted CT denoising via text-guided diffusion and fidelity maintenance.

Ye Shen1, Ningning Liang1, Ailong Cai1

  • 1Department of Henan Key Laboratory of Imaging and Intelligent Processing, Information Engineering University, Zhengzhou, China.

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|March 12, 2026
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Summary

A new Visual-Language Model-assisted CT Denoising (VLD) framework reduces noise in computed tomography (CT) scans without needing paired data. This method improves image quality and diagnostic fidelity for safer patient imaging.

Keywords:
computed tomographydiffusion modelsimage denoisingprompt engineeringvisual language model

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Area of Science:

  • Medical Imaging
  • Artificial Intelligence
  • Image Processing

Background:

  • Reducing radiation dose in computed tomography (CT) and photon-counting CT (PCCT) is vital for patient safety.
  • Low-dose CT imaging introduces noise, degrading image quality and potentially impacting diagnostic accuracy.
  • Current denoising methods often require paired data or rely on specific noise assumptions, limiting clinical applicability.

Purpose of the Study:

  • To introduce a novel Visual-Language Model-assisted CT Denoising (VLD) framework for effective CT image noise reduction.
  • To leverage semantic understanding from visual-language models for improved CT image restoration.
  • To preserve diagnostic fidelity and structural integrity in low-dose CT images.

Main Methods:

  • Developed a Visual-Language Model-assisted CT Denoising (VLD) framework utilizing semantic guidance.
  • Employed a diffusion model guided by semantic understanding derived from multimodal visual-language models.
  • Implemented a tri-domain consistency framework for progressive refinement of image details and structural preservation.

Main Results:

  • The VLD method demonstrated high-quality reconstruction on simulated CT and real PCCT data.
  • Achieved average peak signal-to-noise ratio improvements of 0.95 dB and 1.21 dB under specific conditions.
  • Outperformed existing methods like WGAN and FBPConvNet, which require paired data, in simulation experiments.
  • Showcased robust generalization capabilities to new imaging scenarios.

Conclusions:

  • The VLD framework effectively reduces noise in CT images while maintaining diagnostic quality.
  • Leveraging visual-language models offers a promising direction for advanced medical image denoising.
  • The proposed method provides a robust and generalizable solution for low-dose CT denoising, overcoming limitations of previous approaches.