Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Raman Spectroscopy Instrumentation: Overview01:26

Raman Spectroscopy Instrumentation: Overview

1.6K
A conventional Raman spectrophotometer includes a laser source, a sample holding system, a wavelength selector, and a detector.
The monochromatic laser source, typically using visible or near-infrared radiation, generates a highly focused beam of light. This light interacts with the molecules of the sample, scattering some of the light. Liquid and gaseous samples are usually tested in ordinary glass capillaries, while solids can be analyzed as powders packed in capillaries or as potassium...
1.6K
Raman Spectroscopy: Overview01:20

Raman Spectroscopy: Overview

2.2K
The underlying principle of Raman spectroscopy is based on the interaction between light and matter, specifically molecules' inelastic scattering of photons. When a monochromatic beam of light, typically from a laser source, interacts with a sample, most scattered light has the same frequency as the incident light. This is known as Rayleigh scattering.
However, a small fraction of the scattered light exhibits a frequency shift due to the exchange of energy between the incident photons and...
2.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Fluorescence Signatures of Rare Earth Metals during Precipitation in Various Conditions.

Langmuir : the ACS journal of surfaces and colloids·2026
Same author

Automated pH Monitoring and Control of TALSPEAK and Advanced TALSPEAK Processes.

Analytical chemistry·2025
Same author

Real-Time Automated pH Control within Batch Processes Relying on Raman pH Measurement.

ACS omega·2025
Same author

Developing Fluorescence-Based Sensors to Support Rare Earth Element Separation.

ACS sensors·2025
Same author

Spectroscopic Online Monitoring: Using a Multi-Track Visible Spectrometer to Facilitate a Mass Balance Study in a Simulated TALSPEAK Process.

ACS omega·2025
Same author

Development of an Attenuated Total Reflectance-Ultraviolet-Visible Probe for the Online Monitoring of Dark Solutions.

ACS sensors·2024
Same journal

Machine Learning-Assisted Nanopore for Enhanced Fingerprinting Analysis of Functional Glycans.

Analytical chemistry·2026
Same journal

Correction to "Maleylpyruvic Acid-Inducible Gene Expression System and Its Application for the Development of Gentisic Acid Biosensor".

Analytical chemistry·2026
Same journal

Computer-Aided Rational Hapten Design for Broad-Spectrum Monoclonal Antibody Development against Anthraquinones and Its Application in Lateral Flow Immunoassay.

Analytical chemistry·2026
Same journal

One-Step Chemoenzymatic Labeling and Oxime-Reversible Enrichment for O-GlcNAcylation Profiling under Oxidative Stress.

Analytical chemistry·2026
Same journal

Acid/NIR Dual-Responsive Nanoplatform with AND Logic-Gated Controlled Nitric Oxide Release for Companion Theranostics of Tumors.

Analytical chemistry·2026
Same journal

Multicharged Foldable Plasma Membrane Probes for Precise Cancer Cell Discrimination and Fluorescence-Guided Surgery.

Analytical chemistry·2026
See all related articles

Related Experiment Video

Updated: Mar 14, 2026

Ultrafast Time-resolved Near-IR Stimulated Raman Measurements of Functional π-conjugate Systems
09:57

Ultrafast Time-resolved Near-IR Stimulated Raman Measurements of Functional π-conjugate Systems

Published on: February 10, 2020

7.7K

Raman Spectroscopic In Situ Monitoring of Highly Turbid Media.

Heather M Felmy1, Nikolas T C Boily1, Adan Schafer Medina1

  • 1Pacific Northwest National Laboratory, Richland, Washington 99354, United States.

Analytical Chemistry
|March 12, 2026
PubMed
Summary
This summary is machine-generated.

Close-focus Raman probes enable efficient chemical monitoring in turbid nuclear waste solutions. Advanced data science models accurately quantify nitrate, nitrite, and phosphate, paving the way for online process control.

More Related Videos

Real-time Monitoring of Reactions Performed Using Continuous-flow Processing: The Preparation of 3-Acetylcoumarin as an Example
09:56

Real-time Monitoring of Reactions Performed Using Continuous-flow Processing: The Preparation of 3-Acetylcoumarin as an Example

Published on: November 18, 2015

10.4K
A Novel Technique for Raman Analysis of Highly Radioactive Samples Using Any Standard Micro-Raman Spectrometer
07:52

A Novel Technique for Raman Analysis of Highly Radioactive Samples Using Any Standard Micro-Raman Spectrometer

Published on: April 12, 2017

13.4K

Related Experiment Videos

Last Updated: Mar 14, 2026

Ultrafast Time-resolved Near-IR Stimulated Raman Measurements of Functional π-conjugate Systems
09:57

Ultrafast Time-resolved Near-IR Stimulated Raman Measurements of Functional π-conjugate Systems

Published on: February 10, 2020

7.7K
Real-time Monitoring of Reactions Performed Using Continuous-flow Processing: The Preparation of 3-Acetylcoumarin as an Example
09:56

Real-time Monitoring of Reactions Performed Using Continuous-flow Processing: The Preparation of 3-Acetylcoumarin as an Example

Published on: November 18, 2015

10.4K
A Novel Technique for Raman Analysis of Highly Radioactive Samples Using Any Standard Micro-Raman Spectrometer
07:52

A Novel Technique for Raman Analysis of Highly Radioactive Samples Using Any Standard Micro-Raman Spectrometer

Published on: April 12, 2017

13.4K

Area of Science:

  • Analytical Chemistry
  • Spectroscopy
  • Chemometrics

Background:

  • Efficient chemical processing is crucial for critical materials recovery and nuclear waste cleanup.
  • Online monitoring sensors provide real-time feedback to enhance efficiency and decision-making.
  • Turbid matrices pose challenges for optical spectroscopy due to light scattering and absorption.

Purpose of the Study:

  • To investigate close-focus Raman probes for monitoring chemical compositions in turbid media.
  • To develop chemometric models for quantifying key analytes in challenging matrices.
  • To establish a foundation for online monitoring capabilities in nuclear waste processing.

Main Methods:

  • Utilized close-focus Raman probes to mitigate signal loss in turbid solutions.
  • Employed advanced data science techniques for chemometric model development.
  • Analyzed solutions with solids loadings up to 20 wt %.

Main Results:

  • Accurate quantification of nitrate (NO3-), nitrite (NO2-), and phosphate (PO43-) was achieved.
  • Demonstrated effective performance in highly turbid solutions.
  • Established offline measurement protocols for complex matrices.

Conclusions:

  • Close-focus Raman spectroscopy is a viable technique for analyzing turbid chemical systems.
  • Chemometric modeling enhances the accuracy of analyte quantification in challenging samples.
  • This research supports the development of online monitoring for improved nuclear waste management.