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Related Concept Videos

Autoimmune Disorders01:29

Autoimmune Disorders

2.1K
Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune...
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Diseases of the Liver and Gallbladder01:26

Diseases of the Liver and Gallbladder

2.2K
Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
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Gastritis-II: Pathophysiology01:17

Gastritis-II: Pathophysiology

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Gastritis is marked by disruption of the mucosal barrier that usually protects the stomach tissue from digestive juices and manifests in acute and chronic forms.
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
1.7K

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Related Experiment Video

Updated: Mar 14, 2026

Induction of Drug-Induced, Autoimmune Hepatitis in BALB/c Mice for the Study of Its Pathogenic Mechanisms
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Autoimmune Hepatitis and Pregnancy: A Case Report.

Sayali Tulpule1, Vinit Shah2, Chaitanya Ganapule3

  • 1Consultant Physician, Department of Medicine, Poona Hospital & Research Centre, Pune, Maharashtra, India.

The Journal of the Association of Physicians of India
|March 12, 2026
PubMed
Summary

Autoimmune hepatitis (AIH) in pregnancy requires prompt diagnosis and management. Early identification and care are crucial for successful maternal and fetal outcomes in women with this chronic liver disease.

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Area of Science:

  • Hepatology
  • Immunology
  • Obstetrics

Background:

  • Autoimmune hepatitis (AIH) is a chronic liver disease causing inflammation and necrosis.
  • AIH can progress to fibrosis, cirrhosis, and liver failure.
  • The condition disproportionately affects young to middle-aged women and can exacerbate during pregnancy.

Purpose of the Study:

  • To raise awareness among healthcare professionals regarding AIH in pregnancy.
  • To highlight the importance of timely diagnosis and management for improved maternal and embryonic outcomes.
  • To present a case report of AIH diagnosed during early gestation.

Main Methods:

  • Case report presentation.
  • Review of relevant literature on AIH in pregnancy.
  • Clinical case analysis of a primigravida diagnosed at 14 weeks gestation.

Main Results:

  • The case report details a primigravida diagnosed with AIH at 14 weeks of pregnancy.
  • The report underscores the potential for AIH to cause significant maternal and embryonic complications.
  • Successful management strategies are implied for positive outcomes.

Conclusions:

  • Autoimmune hepatitis is a critical consideration in pregnant women, especially those presenting with liver abnormalities.
  • Early diagnosis and multidisciplinary management are essential for optimizing maternal and fetal health.
  • Increased awareness can lead to better patient care and outcomes for AIH during gestation.