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Evaluation of the Effects of Micro-osteoperforation and Injectable Platelet-rich Fibrin on the External Root
Priyanka Niranjane1, Kushal P Taori2, Krushnali Kolhatkar3
1Department of Orthodontics and Dentofacial Orthopedics, Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Higher Education and Research, Sawangi, Wardha, Maharashtra, India, Phone: +91 9823449728, e-mail: priyankaniranjane10@gmail.com, Orcid: https://orcid.org/0000-0002-4766-2947.
Aim:
To evaluate and compare the effects of micro-osteoperforations (MOPs) and injectable platelet-rich fibrin (I-PRF) on external apical root resorption (EARR) during maxillary canine retraction using a split-mouth prospective study design.
Materials And Methods:
Twenty orthodontic patients (mean age 22.8 ± 2.7 years) who required first premolar extractions bilaterally were recruited. In each subject, one quadrant was randomly assigned to MOP and the contralateral quadrant to I-PRF. All patients underwent fixed appliance therapy with a pre-adjusted edgewise system, and maxillary canines were retracted with NiTi closed-coil springs delivering 150 gm of force. Micro-osteoperforations were performed at the initiation of retraction, whereas I-PRF was injected monthly. To measure changes in root length, cone-beam computed tomography (CBCT) images of the patients were taken both prior to and following full canine retraction (T0 and T1, respectively). Statistical analysis was completed using unpaired and paired t-tests (p < 0.05).
Results:
Both groups demonstrated significant root length reduction after retraction (p < 0.05). The mean EARR in the MOP group was 1.21 ± 0.25 mm, while the I-PRF group showed 1.00 ± 0.10 mm of resorption. Despite the MOP group's somewhat higher resorption, there were no clinically noteworthy distinctions between the two categories (p > 0.05).
Conclusion:
Micro-osteoperforations and I-PRF are both effective adjuncts for facilitating orthodontic tooth movement (OTM); however, both approaches are associated with measurable root resorption. There is no statistically significant difference observed between the two techniques in terms of minimizing EARR.
Clinical Significance:
While MOPs and I-PRF can shorten treatment duration, clinicians should remain cautious of their potential to induce root resorption. Injectable PRF may offer additional biological benefits owing to its regenerative properties, but long-term studies with larger samples should be done before definitive clinical recommendations are suggested. How to cite this article: Niranjane P, Taori KP, Kolhatkar K. Evaluation of the Effects of Micro-osteoperforation and Injectable Platelet-rich Fibrin on the External Root Resorption: A Split-mouth Prospective Study. J Contemp Dent Pract 2026;27(1):78-82.
