Related Experiment Video
Updated: Mar 15, 2026

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry
Published on: June 21, 2018
Mixtum: a graphical tool for two-way admixture analysis in population genetics based on f-statistics
José-María Castelo1, José-Angel Oteo2,3, Gonzalo Oteo-García4,5,6
1Instituto de Ciencia de los Materiales (ICMUV), Universitat de València, Paterna 46980, Spain.
Summary:
Mixtum is a Python-based code that estimates ancestry contributions in a process of two-way admixture based on bi-allelic genotype data. The outcomes of Mixtum come from the geometric interpretation of the f-statistics formalism. Designed with user-friendliness as a priority, Mixtum allows to interactively handle a menu of user-supplied populations to build different mixture models in conjunction with the set of auxiliary populations required by the framework. The results are presented graphically and numerically. Importantly, Mixtum provides a novel index (an angle) that assesses the quality of the ancestral reconstruction of the model under scrutiny. The use and interpretation of the outcomes of Mixtum are explained and illustrated with case studies.
Availability And Implementation:
The open source code is available on GitHub at https://github.com/jmcastelo/mixtum and on Zenodo at https://doi.org/10.5281/zenodo.17789375. Mixtum is implemented in Python and runs on Linux, Windows and macOS.
More Related Videos
06:18Frequency and Distribution of Crossovers in Caenorhabditis elegans Meiosis by SNP Genotyping using Real-time PCR
Published on: July 11, 2025
10:33Multi-locus Variable-number Tandem-repeat Analysis of the Fish-pathogenic Bacterium Yersinia ruckeri by Multiplex PCR and Capillary Electrophoresis
Published on: June 17, 2019
Related Concept Videos
Test for Homogeneity
Hardy-Weinberg Principle
Distributions to Estimate Population Parameter
Mutation, Gene Flow, and Genetic Drift
Chi-square Analysis
The chi-square test was developed by Pearson in 1990.
The first step of performing a Chi-square analysis is to establish a null hypothesis, which assumes that there is no real...
What is Population Genetics?