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Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
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Perinatal Mood Disorders in Polish Women: A Cross-Sectional Study
Mariola Mróz1, Agnieszka Marcewicz1, Malwina Rezwow2
1Department of Specialist Care in Obstetric, Faculty of Health Sciences, Medical University of Lublin, 4-6 Staszica St., 20-081 Lublin, Poland.
Journal of Clinical Medicine
|March 14, 2026
Summary
Women
Area of Science:
- Perinatal mental health
- Reproductive psychiatry
- Women's health
Background:
- Mood disorders are prevalent in perinatal women.
- Emotional well-being and quality of life are crucial during pregnancy and postpartum.
- Integral health monitoring necessitates assessing these factors.
Purpose of the Study:
- To assess emotional disorders and quality of life in pregnant and postpartum women.
- To investigate the relationship between mood disorder symptoms and quality of life.
- To identify obstetric factors influencing mental health outcomes.
Main Methods:
- Cross-sectional study of 400 women in Poland (172 pregnant, 228 postpartum).
- Utilized diagnostic surveys including the SF-36 and Patient Health Questionnaire-9 (PHQ-9).
Main Results:
- Significant negative correlations found between PHQ-9 (depression symptoms) and SF-36 (quality of life) scores.
- Obstetric factors demonstrated a significant impact on both SF-36 and PHQ-9 scores (p < 0.05).
Conclusions:
- Perinatal mood disorder risk is linked to conception duration, pregnancy course, and hospitalizations.
- Depressive symptoms negatively affect women's quality of life during the perinatal period.
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