Related Experiment Video
Updated: Mar 15, 2026

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
Published on: April 12, 2021
Factors associated with non-adherence to antidiabetic medication: A single-centre study in South Punjab, Pakistan
Allahdad Khan1, Urwa Ashfaq2, Beshair Aziz2
1Final Year MBBS Student, Nishtar Medical University, Multan, Pakistan.
Objective:
To identify and evaluate key barriers to medication adherence among diabetes mellitus patients.
Methods:
The descriptive, cross-sectional study was conducted at Nishtar Hospital, Multan, Pakistan, from November 5 to December 10, 2024, and comprised diabetic inpatients aged at least 20 years. Data was collected using a predesigned questionnaire based on the Hill Bone Medication Adherence Scale. Data was analysed using SPSS 23.
Results:
Of the 176 patients with mean age 51±8.6 years (range: 22-73 years), 92(52.3%) were females and 84(47.7%) were males. Factors having a significant association with non-adherence to anti-diabetes medication were age >60 years, monthly salary >50,000 Pak rupee, family history of diabetes, multiple doses, duration of diabetes 5 years or more, and education level beyond high school (p<0.05). Gender and the route of administration had no significant association with nonadherence (p>0.05).
Conclusion:
Diabetic patients with higher income, family history and education were found to have better medication adherence, while advanced age and multiple doses decreased adherence.
Related Concept Videos
Factors Affecting Protein-Drug Binding: Patient-Related Factors
Age stands as a key determinant in protein-drug binding. Neonates, characterized by low albumin content, experience heightened concentrations of unbound drugs such as phenytoin and...
Diabetes Mellitus: Type 2 and Gestational
Diabetes Mellitus: Overview and Type I Subtype
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Drug Toxicity: Risk factors
Therapeutic Drug Monitoring: Affecting Factors
Factors Affecting Protein-Drug Binding: Drug-Related Factors
One crucial factor in drug-protein binding is the drug's lipophilicity or its affinity for fat. More lipophilic drugs tend to have higher binding extents. For example, highly lipophilic drugs like cloxacillin exhibit substantial protein binding, with as much as 95% of the drug binding to proteins. In...

