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Related Experiment Video

Updated: Mar 16, 2026

Author Spotlight: Accessible M&M-Based Mouse Model for Investigating Binge Eating Disorder - Insights into Eating Behaviors, Anxiety, and Neural Mechanisms
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Profiling decision-making mechanisms in binge eating disorder.

Emily Colton1,2, Chanel Agosta3,4, Holly Carey3,4

  • 1School of Psychological Sciences, Monash University, Level 6, 18 Innovation Walk, Clayton, VIC, 3800, Australia. emily.colton@monash.edu.

Journal of Eating Disorders
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Summary

Individuals with binge eating disorder (BED) exhibit generalized decision-making dysfunction and poor psychological functioning. These cognitive and psychological factors are key mechanisms underlying BED, informing new treatment approaches.

Keywords:
Binge eating disorderCognitive functioningDecision-makingImpulsivityPsychological traits

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Area of Science:

  • Neuroscience
  • Psychiatry
  • Cognitive Psychology

Background:

  • Binge eating disorder (BED) is a prevalent mental health condition linked to significant health issues and reduced quality of life.
  • Disordered decision-making is implicated in BED, but the precise cognitive mechanisms are not fully understood.

Purpose of the Study:

  • To investigate decision-making processes across three stages: preference formation, choice implementation, and feedback processing in individuals with BED.
  • To examine the role of psychological factors, including negative emotionality, eating-related tendencies, and impulsivity, in decision-making within BED.

Main Methods:

  • A comparative study involving individuals with BED (n=57), higher weight controls (HWC, n=54), and lower weight controls (LWC, n=54).
  • Utilized profile analyses on cognitive measures of decision-making and assessed psychological functioning domains.

Main Results:

  • Generalized decision-making dysfunction was observed in the BED group compared to the LWC group, independent of BMI.
  • Poor psychological functioning, particularly depressive symptoms and lack of perseverance, significantly differentiated BED from both control groups.

Conclusions:

  • Domain-general cognitive dysfunction, alongside psychological features, represents a crucial mechanism in BED.
  • Findings support refining etiological models of BED and developing personalized treatment strategies.