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Updated: Mar 17, 2026

Indirect Immunofluorescence on Frozen Sections of Mouse Mammary Gland
Published on: December 1, 2015
A Rare Encounter: Mammary-Like Gland Tissue in an Anal Polyp
Laci-Rae Pitter1, Sania L Siddiqui2, Daniel Tomer1
1College of Allopathic Medicine, Nova Southeastern University Dr. Kiran C. Patel College of Allopathic Medicine, Fort Lauderdale, USA.
Abstract:
Anogenital mammary-like glands (AGMLGs) are normal structures in the anogenital region that can undergo pathologic changes similar to breast tissue. This case report presents a 54-year-old female with a complaint of worsening anorectal pain. Her initial physical exam revealed a 1 cm anal polyp. Pathology confirmed breast-like polypoid tissue with benign features, including intraductal papilloma, apocrine metaplasia, and fibrocystic change. The novelty of this case highlights that mammary-like glands can be found outside of the mammary line and may mimic lesions identical to counterparts in the native female breast, underlining that confirmation of diagnosis with histologic evaluation is crucial for management of rare benign and potentially malignant pathologies. Benign lesions can be conservatively excised or monitored based on symptoms and patient preference.
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