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![[DPEPhosbcpCu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F59739.jpg&w=3840&q=50)
[DPEPhosbcpCu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst
Published on: May 21, 2019
Sustainable Synthesis of N-Substituted Pyrroles via Fe-Catalyzed One-Pot Multicomponent Reaction
Santana Chakraborty1, Arijit Singha Mohapatra1, Nanda D Paul1
1Department of Chemistry, Indian Institute of Engineering Science and Technology, Shibpur, Botanic Garden, Howrah 711103, India.
Abstract:
Herein, we present a one-pot strategy for synthesizing N-substituted pyrroles from readily accessible feedstocks, such as alcohols, diols, and amines, catalyzed by a well-defined Fe(II)-catalyst featuring a redox-active azo-aromatic-1,10-phenanthroline-based ligand. Compared to existing approaches, this protocol enables access to diverse pyrrole derivatives, including penta-substituted pyrroles and complex polycyclic frameworks in good yields with improved atom economy and broad functional-group tolerance.
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