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Advanced Hemodynamic Monitoring During Postresuscitation Care After Out-of-Hospital Cardiac Arrest: Protocol for a
Johannes Grand1, Frederik Færgemann Lau1, Christian Hassager1
1Department of Cardiology, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark.
Advanced hemodynamic monitoring in out-of-hospital cardiac arrest (OHCA) survivors is crucial for improving outcomes. This review maps current evidence and identifies gaps in hemodynamic profiling during post-ROSC care.
Area of Science:
- Critical Care Medicine
- Cardiovascular Research
- Hemodynamics
Background:
- Out-of-hospital cardiac arrest (OHCA) survivors face high mortality and neurological deficits.
- Post-resuscitation care often involves managing myocardial dysfunction, vasoplegia, and shock.
- Arterial blood pressure alone is insufficient for assessing tissue perfusion.
Purpose of the Study:
- To map evidence on advanced hemodynamic monitoring in early post-ROSC care for adult OHCA.
- To characterize measured hemodynamic variables, timing, methods, and clinical contexts.
- To identify methodological gaps in hemodynamic monitoring research.
Main Methods:
- Scoping review of adult OHCA patients with sustained return of spontaneous circulation (ROSC).
- Inclusion of studies using advanced invasive or non-invasive hemodynamic monitoring (beyond arterial pressure).
- Exclusion of pediatric, animal, simulation, and echocardiography-only studies.
- MEDLINE search (PubMed) from inception to January 31, 2026, with dual reviewer screening and descriptive synthesis.
Main Results:
- This section is to be filled after the review is completed.
Conclusions:
- The review will offer a comprehensive overview of advanced hemodynamic monitoring post-OHCA.
- It will highlight existing evidence and research gaps in this critical area.
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