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Related Concept Videos

The Effect of Aging on Tissues01:19

The Effect of Aging on Tissues

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Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
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Tissue Renewal without Stem Cells01:23

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After cellular or tissue damage, the resident stem cells present in the human body can locally repair and regenerate the damaged tissue or organ. However, even though some tissues do not have stem cells, they can repair and regenerate with the help of pre-existing cells. For example, beta cells of the pancreas and hepatocytes of the liver can divide to renew and regenerate the tissue. Here, both cell division and cell death are well regulated by homeostasis.
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Aging01:26

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Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
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Renewal of Skin Epidermal Stem Cells01:12

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The skin is divided into epidermis, dermis, and hypodermis, the skin's outermost, middle, and inner layers. The human epidermal layer regularly undergoes renewal, where old, dead cells are replaced by new cells. Epidermal stem cells or EpiSCs divide and differentiate to restore the lost cells. For the renewal process, some EpiSCs continuously self-renew. In contrast, few others differentiate into transit-amplifying cells, which later form prickle or spinous cells, followed by granular...
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Related Experiment Video

Updated: Mar 19, 2026

Author Spotlight: Advancing Facial Rejuvenation Therapy with Post-Laser Salicylic Acid Application
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Aging Face Rejuvenation: Guiding Anatomic and Scientific Concepts.

Rod J Rohrich, Matthew Novak, Nishant Ganesh Kumar

    Aesthetic Surgery Journal
    |March 17, 2026
    PubMed
    Summary

    Facial rejuvenation involves understanding aging in skin and soft tissues. This review details scientific changes and treatment options for effective facial renewal.

    Area of Science:

    • Aesthetic medicine and surgery
    • Dermatology
    • Plastic surgery

    Background:

    • Facial rejuvenation is a highly sought-after aesthetic procedure.
    • Interest in rejuvenation is increasing, even at younger ages, due to new technologies.
    • Both non-invasive methods and surgical techniques like facelifts are evolving.

    Purpose of the Study:

    • To provide a scientific overview of facial aging.
    • To assess changes in various facial layers, focusing on soft tissue and skin.
    • To guide the selection of optimal treatment plans based on facial aging science.

    Main Methods:

    • Review of scientific literature on facial aging.
    • Assessment of anatomical and histological changes in facial tissues.
    • Emphasis on skin and soft tissue alterations.

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    Main Results:

    • Detailed analysis of age-related changes in the face.
    • Identification of key factors contributing to facial aging.
    • Correlation of aging processes with available rejuvenation interventions.

    Conclusions:

    • Anatomical and scientific understanding is crucial for effective facial rejuvenation.
    • Comprehensive assessment of facial aging informs treatment strategies.
    • The article emphasizes soft tissue and skin rejuvenation in the context of aging.