Enhancing conventional biopsies: ultrasound-guided percutaneous bone marrow biopsy and aspiration

To determine the efficacy of ultrasound (US)-guided bone marrow biopsy technique.

The study retrospectively analyzed patients who underwent percutaneous bone marrow core biopsy and aspiration at a single institution from January 2017 to June 2024. Success metrics included lack of patient grievances, precision of sample acquisition, and technical procedural success.

A sample population of 254 was composed of 150 males (median age of 63 years) and 104 females (median age of 63 years). The median (range) BMI was 27.08 (15.31-50.17) for males and 28.79 (17.17-54) for females. The technique achieved 100% accuracy rate with no procedure failures or adverse events reported. Samples collected were viable for pathology assessment. Procedure times ranged from 5 to 30 min. The biopsy was used in various diagnosis of histopathological disease processes. There were no reported dry taps on aspiration.

US-guided percutaneous bone marrow biopsy and aspiration emerges as a promising technique, offering numerous advantages over traditional palpated landmark, fluoroscopic and CT-guided approaches. With its ability to provide real-time guidance, avoidance of ionizing radiation, and comprehensive evaluation of adjacent soft tissues and neurovascular structures, US-guided bone biopsy holds significant promise as an alternative to earlier methods.