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An exploratory ATR-FTIR spectroscopic study of serum protein structural alterations in oral squamous cell carcinoma

Kalpani Senevirathna1,2, Achintha Harshamal Francis3, Mehmood Pirzada4

  • 1Department of Biochemistry, Faculty of Medicine, Uva Wellassa University of Sri Lanka, Badulla, Sri Lanka.

BMC Cancer
|March 18, 2026
PubMed
Abstract

No abstract available in PubMed .

Keywords:
ATR-FTIRAmide I peakOPMDOral cancerProtein conformational changesSerumSpectral fitting

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Attenuated total reflectance (ATR) infrared spectroscopy is a powerful analytical technique used to study the composition of materials. It is widely employed in chemistry, materials science, forensic science, and other fields where sample characterization is required. ATR has several advantages over traditional transmission IR spectroscopy, including the requirement of little to no sample preparation and the ability to analyze a wide range of samples.
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