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Updated: Mar 19, 2026

Loss- and Gain-of-function Approach to Investigate Early Cell Fate Determinants in Preimplantation Mouse Embryos
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TRIM7-mediated autophagy-lysosomal signaling is essential for preimplantation development in mice

Sarmir Khan1,2, Fen Yan1,2, Wenbo Li1,2

  • 1The First Affiliated Hospital, Institute of Reproductive Health, Zhengzhou University, Henan Academy of Innovations in Medical Science, Zhengzhou, Henan, 450000, China.

Journal of Translational Medicine
|March 18, 2026
PubMed
Abstract

No abstract available in PubMed .

Keywords:
Developmental arrestE3 ubiquitin ligaseKnockdownLysosomal-autophagic pathwaysMorpholino rapamycin rescueMouse early embryo

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