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Decoding the circRNA-miRNA-mRNA regulatory network in hepatitis B virus-driven hepatocellular carcinoma

Kainat Ahmed1, Anwaruddin Mohammad2,3, Nan Chaiyariti1

  • 1Department of Physiological Sciences, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK, USA.

Cell Communication and Signaling : CCS
|March 18, 2026
PubMed
Summary

This study identifies a novel circRNA-miRNA-mRNA axis, circADGRL2-miR-361-5p-BDNF, in hepatitis B virus-associated hepatocellular carcinoma (HBV-HCC). This axis may serve as a prognostic biomarker for HBV-HCC patients, aiding in early diagnosis and improved outcomes.

Keywords:
Hepatitis-B VirusHepatocellular CarcinomacircRNAmiRNA

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