Related Experiment Video
Updated: May 13, 2026

Sequencing of Bacterial Microflora in Peripheral Blood: our Experience with HIV-infected Patients
Published on: June 11, 2011
Implementation of HIV pre-exposure prophylaxis (PrEP) in Italy (2023-2024): Results from the PrIDE cohort survey
Silvia Nozza1, Thomas Masoero2, Alessandro Tavelli3
1Infectious Diseases, Vita-Salute San Raffaele University, Milano, Italy; Infectious Diseases Unit, IRCCS San Raffaele Scientific Institute, Milano, Italy.
Objectives:
Italy introduced reimbursement for oral HIV pre-exposure prophylaxis (PrEP) in 2023. We examined PrEP implementation in Italy from 2023 to 2024 to evaluate regional uptake.
Methods:
A nationwide survey within the scope of the PrIDE cohort (NCT07186244) was conducted across 62 infectious diseases and community-based centers in Italy in 2023 and 2024. Data were collected on individuals who started PrEP and those in follow-up, demographics, and the people with HIV (PWH) to PrEP users ratio, as proxy for unmet prevention need. We compared metrics before and after PrEP reimbursement and analyzed regional disparities.
Results:
PrEP uptake increased substantially in 2024, with a cumulative number of users increasing by 51.6% (10,697 in 2023, 16,220 in 2024). Growth was uneven across regions: Sardinia (+71.4%), Friuli (+65.4%), and Emilia-Romagna (+54.7%) experienced the most significant increases. Most PrEP users remain concentrated in certain regions (Lombardy, Lazio, and Emilia-Romagna accounting for 75.6%) and were male (95.7%). Overall, 11,785/16,220 (72.7%) individuals were retained in care through 2024. The PWH/PrEP ratio improved nationally in 2024, but remained high in some areas.
Conclusion:
The PrIDE survey shows an increase in PrEP uptake and services expansion after reimbursement in Italy. However, significant regional disparities and structural barriers endure.
Related Concept Videos
Healthcare Associated Infections II: Preventive Measures
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
Clinical Trials
There are four phases in a clinical trial. A phase one...
Pharmacovigilance
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
Preclinical Development: Overview
Sexually Transmitted Infections
Study Designs in Epidemiology
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and case-control studies.

