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Updated: Mar 19, 2026

Author Spotlight: Functionalizing Metal-Organic Frameworks: Advancements, Challenges, and the Power of Post-Synthetic Ligand Exchange
Published on: June 23, 2023
Rational integration of fluorine and hydroxyl functionalities in UiO-66 metal-organic framework for enhanced
Yao-Ting Wang1,2, Yu-Tung Chou1,2, Po-Chuan Chao1,2
1Department of Chemical Engineering, National Cheng Kung University, Tainan City 70101, Taiwan. wkaveechai@mail.ncku.edu.tw.
None:
Zr-based metal-organic framework UiO-66 is an attractive platform for hydrocarbon separations due to its exceptional chemical and thermal stability. We report a new UiO-66 derivative, UiO-66-F2(OH)2, integrating fluorine and hydroxyl groups into the framework. Compared to UiO-66-F4 and UiO-66-(OH)2, the coexistence of these two functionalities tunes the pore environment, resulting in enhanced differentiation for propylene and propane adsorption. The cyclic breakthrough experiments demonstrate the effective and stable dynamic separation of propylene and propane using UiO-66-F2(OH)2.
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