Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

Open Angle Glaucoma: Treatment

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...

Angle Closure Glaucoma: Treatment

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Visual disability accommodations and ophthalmology.

BMJ open ophthalmology·2026

Same author

Inducing Daytime Circadian Phase Shifts Using Chemogenetic and Spectral Approaches.

Journal of visualized experiments : JoVE·2026

Same author

Vision loss, disability and multimorbidity among older people in Andhra Pradesh and Telangana in South India: the longitudinal eye health, ageing and disability study (LEADS) - study protocol.

BMJ public health·2026

Same author

A Clinically Relevant Threshold of Impaired Contrast Sensitivity Among Older US Adults.

JAMA ophthalmology·2026

Same author

Firecracker injury induced acute secondary angle closure.

Eye (London, England)·2026

Same author

Locally-affiliated authorship in global eye health research conducted in Sub-Saharan Africa between 2003 and 2022.

Eye (London, England)·2026

Same journal

Revealing the Hidden Tube: A Simple Laser Solution in a Complex Eye.

Ophthalmology. Glaucoma·2026

Same journal

Focal Epithelial Bullae at the Air-Cornea Interface After Glaucoma Surgery.

Ophthalmology. Glaucoma·2026

Same journal

Effect of intraocular pressure control on visual field progression in the HORIZON trial.

Ophthalmology. Glaucoma·2026

Same journal

Comparing national microinvasive glaucoma surgery procedure rates in response to Medicare and industry payment changes.

Ophthalmology. Glaucoma·2026

Same journal

Standardized Classification System for Dysphotopsia Reporting.

Ophthalmology. Glaucoma·2026

Same journal

The Flip Sides of Interventional Glaucoma.

Ophthalmology. Glaucoma·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Mar 20, 2026

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

Family Screening in Glaucoma: A Scoping Review.

Annamalai Odayappan¹, Joshua R Ehrlich², Tos Tjm Berendschot³

¹Glaucoma Services, Aravind Eye Hospital, Pondicherry, India; Department of Ophthalmology and Visual Sciences, Kellogg Eye Center, University of Michigan, Ann Arbor, Michigan.

Ophthalmology. Glaucoma

|March 18, 2026

Summary

This summary is machine-generated.

Glaucoma screening for relatives of patients reveals high prevalence of the disease. Direct communication methods significantly improve screening participation rates among family members.

Keywords:

Blindness Family Glaucoma High-risk population Ophthalmology Scoping review Screening

More Related Videos

Laser Capture Microdissection of Highly Pure Trabecular Meshwork from Mouse Eyes for Gene Expression Analysis

Laser Capture Microdissection of Highly Pure Trabecular Meshwork from Mouse Eyes for Gene Expression Analysis

Published on: June 3, 2018

$Subjective Refraction Test Using a Smartphone for Vision Screening$

Subjective Refraction Test Using a Smartphone for Vision Screening

Published on: October 18, 2024

Related Experiment Videos

Last Updated: Mar 20, 2026

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

Laser Capture Microdissection of Highly Pure Trabecular Meshwork from Mouse Eyes for Gene Expression Analysis

Laser Capture Microdissection of Highly Pure Trabecular Meshwork from Mouse Eyes for Gene Expression Analysis

Published on: June 3, 2018

$Subjective Refraction Test Using a Smartphone for Vision Screening$

Subjective Refraction Test Using a Smartphone for Vision Screening

Published on: October 18, 2024

Area of Science:

Ophthalmology
Public Health
Genetics

Background:

Family history is a significant risk factor for glaucoma.
Population-based glaucoma screening faces challenges due to low general prevalence.
Implementing family screening programs for glaucoma is not yet standard practice.

Purpose of the Study:

To determine the prevalence of glaucoma in relatives of diagnosed patients.
To evaluate response rates in glaucoma family screening programs.
To identify barriers to family member participation in screening.

Main Methods:

Systematic literature search across multiple databases (MEDLINE, Embase, Scopus, etc.).
Inclusion of studies on primary open-angle glaucoma, primary angle closure disease, pseudoexfoliation glaucoma, and pigmentary glaucoma.
Analysis focused on response rates and detection of previously undiagnosed glaucoma in relatives.

Main Results:

Median glaucoma prevalence among relatives was 11.25%; glaucoma suspects were 19.45%.
Prevalence varied by relation: offspring (3.4%), siblings (16.2%), and parents (31.6%).
Direct contact (letters, phone) yielded higher response rates (74.6%, 48%) than indirect methods (12.9%).

Conclusions:

Over 30% of relatives of glaucoma patients have glaucoma or are suspects.
Screening programs must prioritize direct engagement with relatives.
Further research is needed on optimal screening age.