Related Experiment Video
Updated: Mar 20, 2026

Use of Interferon-γ Enzyme-linked Immunospot Assay to Characterize Novel T-cell Epitopes of Human Papillomavirus
Published on: March 8, 2012
Lessons Learned From the Implementation of a Clinic-Focused HPV Vaccination Initiative
Idara N Akpan1, Grace Maynard1, Rachel J Meadows2
1University of North Texas Health Science Center, Fort Worth, TX, USA.
Introduction:
Strengthening provider recommendation is an effective strategy in increasing the human papillomavirus (HPV) vaccine uptake. A quality improvement (QI) initiative called "Communicating about HPV to Adults and Teens" (HPV CHAT) was initiated to support providers with communication tools to discuss HPV vaccination with parents and patients. We described lessons learned for implementation of a clinic-based provider training for HPV vaccination.
Methods:
HPV CHAT was implemented in safety-net hospital clinics, practice-based research clinics, and federally qualified health centers between September 2021 and August 2023. Guided by the Plan-Do-Study-Act (PDSA) model, we retrospectively evaluated process improvements across 2 implementation cycles.
Results:
Overall, 318 providers participated across the 2 cycles. Key activities in the first cycle included identification of clinic needs, development of asynchronous virtual training, advisory board feedback, recruitment communications via practice and clinic managers, and provider participation monitoring. Barriers included slow response to participation (58.3% response rate) and high turnover rate in some clinics. Results from the first cycle informed activities implemented in the second cycle. In the second cycle, participation rate was 60.6% and varied across settings due to strength of clinic collaborations and prior knowledge of the implementation process.
Conclusions:
The success of HPV CHAT underscores the need to proactively tailor interventions for clinical settings.
More Related Videos
Related Concept Videos
Cancer Vaccines
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
Primary Healthcare Services
In 1978, international leaders convened in Alma-Ata, Kazakhstan, for what would be a pivotal event in global health. The Alma-Ata Declaration was the first to call...
Preventive Healthcare Services
Vaccinations
Cancer Prevention
Some...
Cancer Prevention

