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Slow-Resorbing Small Intestinal Submucosa Membrane for Horizontal Ridge Augmentation: A Case Series
Mingxu Sun1, Zhaozhao Chen2, Zhen Yang3
1Pingdu Jianbo Dental Hospital, Qingdao, Shandong, China.
Objective:
To evaluate the efficacy of a slow-resorbing small intestinal submucosa (SIS) membrane combined with freeze-dried bone allograft (FDBA) for horizontal bone augmentation in severely atrophic ridges.
Materials And Methods:
Six patients underwent horizontal ridge augmentation using FDBA and a slow-resorbing SIS membrane. Cone-beam computed tomography (CBCT) was used to measure horizontal bone width 2 mm apical to the alveolar crest at preoperatively (T0), immediately postoperatively (T1), and 4-6 months postoperatively (T2). Membrane integrity was assessed at the time of implant placement. Additionally, bone core biopsy was obtained for histomorphometric analyses.
Results:
All surgical sites healed uneventfully. Horizontal bone gain was 4.74 ± 2.00 mm (T2-T0), with minimal resorption (0.37 ± 0.22 mm, T1-T2) and 95.08% ± 3.30% bone retention. Histomorphometry showed 44.6% new bone and 38.1% residual graft. All SIS membranes retained structural integrity at re-entry.
Conclusion:
In this small case series, the SIS-GBR technique, combining a slow-resorbing SIS membrane with FDBA, provided preliminary evidence of substantial horizontal bone gain and favorable biocompatibility, with minimal short-term resorption.
