Related Experiment Video
Updated: Mar 21, 2026

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
Published on: January 21, 2020
Periodontitis Is Associated With Poor Blood Pressure Control in Treated Hypertensive Individuals
Kitti Torrungruang1, Prin Vathesatogkit2, Piyamitr Sritara2
1Department of Microbiology, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand.
Severe periodontitis is linked to uncontrolled hypertension, especially elevated systolic blood pressure (SBP), in treated hypertensive individuals. This highlights a significant association between gum disease and blood pressure management challenges.
Area of Science:
- Cardiovascular Health
- Periodontal Medicine
- Hypertension Research
Background:
- Hypertension is a major risk factor for cardiovascular disease.
- Periodontitis, a common gum infection, has been increasingly linked to systemic health conditions.
- The relationship between periodontitis severity and hypertension control requires further investigation.
Purpose of the Study:
- To examine the association between periodontitis at baseline and uncontrolled hypertension.
- To explore this link across two distinct cohort waves.
Main Methods:
- Periodontitis assessed via categorical (non-severe, localised severe, generalised severe) and continuous measures (mean probing depth, clinical attachment level).
- Uncontrolled hypertension defined as systolic blood pressure (SBP) ≥140 mmHg or diastolic blood pressure (DBP) ≥90 mmHg.
- Mixed-effects logistic regression used to analyze associations, adjusting for confounders.
Main Results:
- 417 treated hypertensive participants (53-73 years) included.
- Severe periodontitis (localised/generalised) associated with higher odds of uncontrolled hypertension (OR 1.56-1.74).
- Severe periodontitis linked to uncontrolled SBP, but not DBP; similar findings for mean PD and CAL.
Conclusions:
- Severe periodontitis is associated with poorer blood pressure control in treated hypertensive patients.
- The primary driver appears to be an increased likelihood of uncontrolled systolic blood pressure (SBP).
- Findings underscore the importance of considering oral health in hypertension management.
Related Concept Videos
Hypertension and Regulation of Blood Pressure
Hypertension I: Introduction
Hypertension II: Pathophysiology
Hypertension III: Clinical Manifestations and Diagnostic Studies
Alterations in Blood Pressure
Hypertension (High blood pressure)
Hypertension occurs when blood pressure readings consistently exceed the normal range. It is diagnosed when systolic blood pressure (the top number, indicating pressure while the heart...
Hypertension V: Nursing Management

