Navigating the Diagnostic Continuum: Feline Lymphoplasmacytic Enteritis and Low-Grade Intestinal T-cell Lymphoma

This article discusses the importance of accurately diagnosing feline gastrointestinal diseases, particularly differentiating inflammatory bowel disease from alimentary lymphoma. It emphasizes that precise diagnosis impacts treatment decisions, prognosis, and research. The review covers diagnostic approaches, including clinical signs, diet trials, imaging, biopsies, histopathology, immunohistochemistry, and molecular testing. It explores the potential progression from chronic inflammation to lymphoma, highlighting similarities with human disease pathways. Ultimately, improved understanding and classification of these diseases will enhance patient management, guide targeted therapies, and advance translational research benefiting both feline and human medicine.