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Characterizing AIDS Drug Assistance Program Practices and Policies for Sustained Viral Suppression Using the
Kathleen A McManus1, Erin Q Rogers1, Amber Steen2
1Division of Infectious Diseases & International Health, School of Medicine, University of Virginia, Charlottesville, VA, United States.
JMIR Research Protocols
|March 20, 2026
Summary
AIDS Drug Assistance Programs (ADAPs) aim to improve viral suppression rates in people with HIV. This study examines operational and policy factors influencing ADAP success to help end the HIV epidemic.
Area of Science:
- Public Health
- Health Services Research
- Implementation Science
Background:
- AIDS Drug Assistance Programs (ADAPs) are crucial for providing antiretroviral therapy (ART) to low-income and uninsured/underinsured people with HIV (PWH).
- ADAPs operate with jurisdictional flexibility, impacting client outcomes like viral suppression rates.
- Despite an 85% national viral suppression rate, the 90% goal to end the HIV epidemic remains unmet, with limited understanding of factors driving success.
Purpose of the Study:
- To qualitatively examine operational, organizational, and contextual factors influencing ADAP effectiveness in improving viral suppression.
- To identify mechanisms enabling high performance and viral suppression for all PWH within ADAPs.
- To inform policy, program, and operational changes for enhanced ADAP design and implementation.
Main Methods:
- A qualitative descriptive approach using the Consolidated Framework for Implementation Research (CFIR).
- Semi-structured interviews with 33 state-level ADAP leaders, decision-makers, and staff across 16 states.
- Analysis of interview data using deductive and inductive approaches with situational mapping.
Main Results:
- Data analysis is currently underway as of March 2026.
- Interviews were conducted between February 12, 2025, and March 20, 2025.
- Participant data includes 33 individuals from 16 states across all four U.S. Census regions.
Conclusions:
- The study anticipates identifying key features, practices, and norms contributing to high viral suppression rates in ADAPs.
- Findings will provide evidence for improving state and federal regulations, program development, and resource allocation.
- Dissemination of results is expected to support enhanced viral suppression, individual health outcomes, and public health objectives.

