Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Mar 21, 2026

A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance
05:19

A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance

Published on: November 7, 2025

1.0K

Active Surveillance for Localized Prostate Cancer: A Retrospective Single-Center Study.

Akihiko Sugino1, Yoshiyuki Miyazawa1, Shun Nakazawa1

  • 1Gunma University Graduate School of Medicine & Gunma University Hospital, Department of Urology, Maebashi, Japan.

International Journal of Urology : Official Journal of the Japanese Urological Association
|March 20, 2026
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Longitudinal changes in DNA methylation in IDH-mutant glioma fuel disease progression through altered cell state differentiation.

Nature genetics·2026
Same author

Aged garlic extract suppressed macrophage-mediated inflammation in acute respiratory distress syndrome.

Food & function·2026
Same author

Systemic immune-inflammation and response indices is associated with early but not long-term survival after primary stereotactic radiosurgery for brain metastases.

British journal of neurosurgery·2026
Same author

Acquired genetic and cell-state changes in IDH-mutant glioma progression.

Nature·2026
Same author

Clinical Utility of Postoperative Day 1 Technetium-99m Mercaptoacetyltriglycine Scintigraphy for Early Assessment of Graft Function in Living Donor Kidney Transplant Recipients.

Journal of transplantation·2026
Same author

Imaging diagnosis of adult-type diffuse gliomas in the era of WHO CNS5 and cIMPACT-NOW updates 8-11: a narrative review.

Japanese journal of radiology·2026
Same journal

Feasibility of Approximate Post-Void Residual Measurement in Children Using Bladder Scanners.

International journal of urology : official journal of the Japanese Urological Association·2026
Same journal

Longitudinal Changes in Overactive Bladder Symptoms After Prostatic Urethral Lift for Benign Prostatic Hyperplasia: A Japanese Single-Center Prospective Study.

International journal of urology : official journal of the Japanese Urological Association·2026
Same journal

Editorial Comment on Prognostic Value of Inflammatory Biomarkers as Continuous Variables in Metastatic Renal Cell Carcinoma: Linearity Assessment, Proportional Hazards Assumption Testing, and Time-Varying Effects.

International journal of urology : official journal of the Japanese Urological Association·2026
Same journal

Editorial Comment on Prevalence and Factors Associated With Nocturia (≥ 2 Night-Time Urinary Episodes) in Japan: Analysis of the 2023 Japan Community Health Survey (JaCS 2023).

International journal of urology : official journal of the Japanese Urological Association·2026
Same journal

Incidence and Risk Factors for Perioperative Infections After Robot-Assisted Radical Prostatectomy: A Multicenter Study.

International journal of urology : official journal of the Japanese Urological Association·2026
Same journal

Editorial Comment on Moriyama et al.: Fully Extraperitoneal Robotic Sacrohysteropexy for Pelvic Organ Prolapse.

International journal of urology : official journal of the Japanese Urological Association·2026
See all related articles
This summary is machine-generated.

Active surveillance for prostate cancer in Japan shows good long-term safety and durability. Improving repeat biopsy adherence can enhance patient management and outcomes.

Area of Science:

  • Urology
  • Oncology
  • Clinical Research

Background:

  • Active surveillance (AS) is a strategy to manage prostate cancer, minimizing overtreatment.
  • Adoption of AS in Japan is limited, necessitating Japan-specific clinical outcome data.
  • This study evaluates the safety and efficacy of AS in a Japanese cohort.

Purpose of the Study:

  • To assess the clinical outcomes of patients with prostate cancer managed under active surveillance (AS) in Japan.
  • To provide institution-specific evidence on AS safety and durability.
  • To identify factors influencing AS persistence and patient adherence to protocols.

Main Methods:

  • Retrospective review of 86 patients who underwent AS between 2012 and 2024.
  • Inclusion criteria: ≤ cT2a disease, PSA ≤ 10 ng/mL, Gleason score 3+3, ≤2 positive cores, with exceptions for GS 3+4 or 4+3 based on preference.
Keywords:
active surveillancelocalizedprostate cancer

More Related Videos

MR Molecular Imaging of Prostate Cancer with a Small Molecular CLT1 Peptide Targeted Contrast Agent
06:54

MR Molecular Imaging of Prostate Cancer with a Small Molecular CLT1 Peptide Targeted Contrast Agent

Published on: September 3, 2013

11.8K
Transperineal Prostate Biopsy Using a Cone-shaped Double-hole Method with Dual-plane Probe Guidance
05:35

Transperineal Prostate Biopsy Using a Cone-shaped Double-hole Method with Dual-plane Probe Guidance

Published on: June 6, 2025

2.1K

Related Experiment Videos

Last Updated: Mar 21, 2026

A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance
05:19

A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance

Published on: November 7, 2025

1.0K
MR Molecular Imaging of Prostate Cancer with a Small Molecular CLT1 Peptide Targeted Contrast Agent
06:54

MR Molecular Imaging of Prostate Cancer with a Small Molecular CLT1 Peptide Targeted Contrast Agent

Published on: September 3, 2013

11.8K
Transperineal Prostate Biopsy Using a Cone-shaped Double-hole Method with Dual-plane Probe Guidance
05:35

Transperineal Prostate Biopsy Using a Cone-shaped Double-hole Method with Dual-plane Probe Guidance

Published on: June 6, 2025

2.1K
  • AS discontinuation criteria: clinical/pathological progression or patient preference; follow-up included repeat biopsies.

    • Main Results:

    • Mean follow-up was 48 months; no prostate cancer-specific deaths occurred.
    • AS persistence rates were 89% (1 year), 55% (5 years), and 27% (10 years). Older age (≥75 years) correlated with longer AS persistence.
    • Pathological upgrading occurred in 35% of repeat biopsies. Acceptance of 1-year repeat biopsy increased from 46% to 64% over time.

    Conclusions:

    • Active surveillance demonstrates favorable long-term safety and durability for prostate cancer management in Japan.
    • Adherence to repeat biopsy protocols is crucial for optimizing AS management.
    • Findings support the feasibility of AS in Japan with potential for wider adoption.